Abstract Background One of the most significant events in recent Afghan history is the rise of the Taliban and the war that followed, which had profound impacts on the lives of Afghans.The present study examined the mental health of Afghans living under the Taliban government.Methods Between June 5, 2023 and February 12, 2024, a cross-sectional stu
Abstract Background Circular RNAs (circRNAs) are stable, often highly expressed RNA transcripts with PS-100 potential to modulate other regulatory RNAs.A few circRNAs have been shown to bind RNA-binding proteins (RBPs); however, little is known about the prevalence and distribution of these interactions in different biological contexts.Methods We c
Iron-sulfur (Fe-S) clusters are inorganic prosthetic groups in proteins composed exclusively of iron and inorganic sulfide.These cofactors are required in a wide range of critical cellular pathways.Iron-sulfur clusters do not form spontaneously in vivo; several proteins are required to mobilize sulfur and iron, assemble and traffic-nascent clusters
Mutations in coding and non-coding regions of FUS cause amyotrophic lateral sclerosis (ALS).The latter mutations may exert toxicity by increasing FUS accumulation.We show here that broad expression USB to Audio Adaptor within the nervous system of wild-type or either of two ALS-linked mutants of human FUS in mice produces progressive motor phenotyp
The article is devoted to the study of the asymptotic Wildbird Feeders behavior of solving an integral boundary value problem for a third - order linear differential equation with a small parameter for two higher derivatives, provided that the roots of the "additional characteristic equation" have opposite signs.In the work are constructed the fund